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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETS1
All Species:
30
Human Site:
Y223
Identified Species:
55
UniProt:
P14921
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14921
NP_005229.1
441
50408
Y223
T
D
T
L
Q
N
D
Y
F
A
I
K
Q
E
V
Chimpanzee
Pan troglodytes
XP_001170891
731
79148
Y513
L
S
S
V
S
V
T
Y
C
S
V
S
Q
D
F
Rhesus Macaque
Macaca mulatta
XP_001113198
441
50116
Y223
T
D
T
L
Q
N
D
Y
F
A
I
K
Q
E
V
Dog
Lupus familis
XP_546405
441
50378
Y223
T
D
T
L
Q
T
D
Y
F
A
I
K
Q
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P27577
440
50183
Y223
T
D
T
L
Q
T
D
Y
F
A
I
K
Q
E
V
Rat
Rattus norvegicus
P41156
441
50404
Y223
T
D
T
L
Q
T
D
Y
F
A
I
K
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508979
473
53725
Y255
L
D
T
V
S
V
N
Y
C
S
V
N
Q
D
F
Chicken
Gallus gallus
P13474
441
50308
Y223
T
D
S
L
Q
T
D
Y
F
T
I
K
Q
E
V
Frog
Xenopus laevis
P18755
438
50249
Y220
P
E
S
L
Q
G
D
Y
F
T
I
K
Q
E
V
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
S223
R
I
D
P
A
H
A
S
G
G
G
G
G
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51022
623
66848
G229
D
V
N
F
F
S
S
G
Y
N
T
S
N
T
H
Honey Bee
Apis mellifera
XP_396368
484
53763
L264
F
T
C
D
V
K
K
L
T
M
D
R
W
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999698
559
62034
F278
D
D
F
L
A
Q
G
F
S
V
D
Q
P
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
95.9
99
N.A.
97
98.8
N.A.
52.2
95.9
88.6
23.4
N.A.
28.4
32
N.A.
38.1
Protein Similarity:
100
43.2
96.8
99.5
N.A.
98.4
99.3
N.A.
66.5
97.7
93.8
37.6
N.A.
41
42.5
N.A.
50.8
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
26.6
80
66.6
0
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
46.6
100
93.3
N.A.
93.3
93.3
N.A.
60
86.6
80
6.6
N.A.
13.3
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
8
0
0
39
0
0
0
0
16
% A
% Cys:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
0
% C
% Asp:
16
62
8
8
0
0
54
0
0
0
16
0
0
16
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
54
0
% E
% Phe:
8
0
8
8
8
0
0
8
54
0
0
0
0
0
16
% F
% Gly:
0
0
0
0
0
8
8
8
8
8
8
8
8
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
54
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
0
54
0
0
0
% K
% Leu:
16
0
0
62
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
16
8
0
0
8
0
8
8
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
54
8
0
0
0
0
0
8
70
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
0
8
24
0
16
8
8
8
8
16
0
16
0
0
0
% S
% Thr:
47
8
47
0
0
31
8
0
8
16
8
0
0
8
0
% T
% Val:
0
8
0
16
8
16
0
0
0
8
16
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _